When Terbinafine was screened against TASK2, TREK2, THIK1, TWIK1 and TRESK no activation was observed in thallium flux assays. In a thallium flux assay a pEC50 of 6.2 ( 0.12) was observed. Find all active bits and calculate the answer respectively //package kg.my_algorithms. After screening a library of 1000 compounds, including drug-like and FDA approved molecules, we identified Terbinafine as an activator of TASK3. Solution to all the subtasks can be found here Tester’s solution:Īnother way of doing this. Solution to sub tasks 1 and 2 can be found here Solution to sub tasks 1 and 3 can be found here “long” datatype is 32 bits in C++ Setter’s solution: Subtask 3: cnt * (cnt-1)/2 will overflow for cnt = 10^5. The maximal possible value of i equals to 29 here, as it is a binary logarithm of maximal possible value in the sequence. Therefore, the final formula is the sum of f(i) * f(i-1)/2 * 2^i over all possible values of i. Generally, there will be f(i)*(f(i)-1)/2 ways to add 2^i to the answer, where f(i) is the number of numbers in the sequence that contain 2^i in their binary representation. Then, there are f(0) * (f(0)-1)/2 ways to add 2^0 to the answer. At first, let’s count the number of nonzero 0-th bits - we will call this number f(0). That gives rise to the following solution: let’s solve the problem bit-by-bit. Another observation is that in some exact bit of the result, AND depends only on this bit in its arguments. Task(process.c, process.task3) 2558 process.task4 cms. Let’s use the observation that we had in sub task 3, AND of two binary values is a natural number only in case both of them are true. process,label) 1433 def newPSet(self): 1434 return TopLevelPSetAcessorAdaptor(self.ppset. ![]() In this sub task the constraints are designed in such a way that you can just do the brute force among all the pairs ( i, j) where i < j and add the value of the i-th number AND the j-th number to the answer. ![]() Naturally, the answer equals to o * (o - 1) / 2, where o is the number of ones in the sequence. Thus, you just have to calculate the number of pairs ( i, j) where i < j and both the i-th and the j-th numbers equal to one. If you take a look at the AND function for all possible pairs of numbers in the sequence - 0,0 0,1 1,0 1,1 - you will notice that AND equals to one only in case both arguments equal to one, otherwise it equals to zero and will not change the answer in any way. Explanation: Solution to the sub tasks 1 and 3: Calculate the sum of A AND A for all the pairs ( i, j) where i < j. ![]() You are given a sequence of N integer numbers A. Binary Notation, Binary AND operation Problem:
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |